The most recent tips of the phylogenetic tree are largely dominated by viruses assigned to XFG, which represent the prevailing lineages among newly deposited North American genomes. These clusters are followed by continued representation of PQ.2 and XFG.1.1, highlighting ongoing diversification within Omicron-derived lineages.
Branching patterns within the tree illustrate how contemporary lineages descend from earlier variants, with mutation accumulation through time supporting molecular clock-based estimates of divergence.
Analysis of recent GISAID submissions indicates that USA, Canada, and Puerto Rico currently contribute the largest number of hCoV-19 (SARS-CoV-2) genome sequences from North America. Extensive sequencing from these countries strengthens phylogenetic resolution and enables detailed examination of transmission dynamics across the region.
Although the analysis is centered on North America, selected genomes from other continents are included to anchor regional patterns within the global hCoV-19 (SARS-CoV-2) phylogeny.
A North America-focused hCoV-19 (SARS-CoV-2) phylogenetic tree supports continuous monitoring of viral evolution in a highly connected region. By integrating genomic data with evolutionary analysis, it provides critical context for understanding lineage turnover and contributes to ongoing genomic surveillance and public health efforts.
For more details see: https://gisaid.org/sars-cov-2-phylogeny/north-america/
